223

NUP62 Antibody | XW-8071

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SKU:
223-XW-8071-GEN
NULL858.00

Description

NUP62 Antibody | XW-8071 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human

Homology: N/A

Immunogen: 328-522

Research Area: Other

Tested Application: WB

Application: Nuclear pore glycoprotein p62 antibody can be used for the detection of Nuclear pore glycoprotein p62 by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 53.3 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: NUP62 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: Nuclear pore glycoprotein p62, 62 kDa nucleoporin, p62, IBSN, SNDI, Nuclear pore glycoprotein p62

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex.

SUBUNIT: Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1 (By similarity)

SUBCELLULAR LOCATION: Nucleus; nuclear envelope; nuclear pore complex. Central region of the nuclear pore, within the transporter. During mitotic cell division, it associates with the poles of the mitotic spindle.

DOMAIN: Contains F-X-F-G repeats.

SIMILARITY: Belongs to the NUP62 family.

SUMMARY: Nuclear pore complexes mediate active transport of protein and RNA through the nuclear envelope. Nucleoporins are glycoproteins that contain N-acetylglucosamine residues O-linked to serine and possibly threonine. They are localized to the central 'transporter' region of the pore complex.

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Additional Information

Size:
0.05 mg
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