OAZ1 polyclonal Antibody | BS61230

OAZ1 polyclonal Antibody | BS61230 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Antizyme 1 (AZ1) negatively regulates polyamine synthesis by enhancing the negative feedback loop controlling ornithine decarboxylase (ODC) activity. Polyamines are involved in cell cycle and cell growth, and thus the interaction between AZ1 and ODC functions in this process as well, in a regulatory manner. Furthermore, treatment of cells with leptomycin B, an inhibitor of chromosomal maintenance proteins, causes the relocation of AZ1 to the nucleus, suggesting a novel function of AZ1 not associated with the proteasome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: OAZ1 polyclonal Antibody detects endogenous levels of OAZ1 protein.

Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Ornithine decarboxylase antizyme 1; ODC-Az; OAZ1; OAZ

Immunogen: A synthetic peptide corresponding to residues in Human OAZ1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: