Occludin Polyclonal Antibody | E-AB-64286

Occludin Polyclonal Antibody | E-AB-64286 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: OCLN, BLCPMG, PPP1R115, PTORCH1, occludin, Occludin

Application: WB, IHC

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human Occludin (NP_002529.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 8 kDa/23 kDa/31 kDa/52 kDa/54 kDa/59 kDa

Molecular Weight(Observed): 68 kDa