OGG1 polyclonal Antibody | BS90982

OGG1 polyclonal Antibody | BS90982 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB:1:500 IHC:1:50-1:200

Background: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.  The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: OGG1 polyclonal Antibody detects endogenous levels of OGG1 protein.

Molecular Weight: 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AP lyase, OGG1, MMH, MUTM, OGH1, 8 hydroxyguanine DNA glycosylase, 8 oxoguanine DNA glycosylase 1, 8 oxoguanine DNA glycosylase, AP lyase, DNA (apurinic or apyrimidinic site) lyase, DNA apurinic or apyrimidinic site lyase, DNA lyase, DNA- (apurinic or apyrimidinic site) lyase, HMMH, HOGG 1, HOGG1, MMH, MUTM, N glycosylase, Ogg 1, Ogg1, OGG1, OGH 1, OGH1,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: