OSI-930 | B1712

OSI-930 is a potent inhibitor of receptor tyrosine kinases with IC50 values of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM for c-Kit, KDR, Flt, CSF-1R, c-Raf and Lck respectively.

OSI-930 is a potent inhibitor of receptor tyrosine kinases with IC50 values of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM for c-Kit, KDR, Flt, CSF-1R, c-Raf and Lck respectively.

B1712 | OSI-930 DataSheet

Alternate Name/Synonyms: OSI-930; OSI930; OSI 930; 3-((quinolin-4-ylmethyl)amino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide

Appearance: Solid

Formulation: N/A

CAS Number: 728033-96-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₁₆F₃N₃O₂S

Molecular Weight: 443.44

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Kit, KDR, Flt, CSF-1R, c-Raf and Lck Inhibitor

MDL Number: NA

PubChem CID: 9868037

SMILES: C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F

InChi: InChI=1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29)

InChi Key: FGTCROZDHDSNIO-UHFFFAOYSA-N