OTC Antibody | 23-932

OTC Antibody | 23-932 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human OTC (NP_000522.3) .

Research Area: Cancer, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:1000 - 1:4000
IHC: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: Mouse liver

Positive Control 2: Mouse small intestine

Positive Control 3: Rat liver

Positive Control 4: Rat small intestine

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 38kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: OTC, OCTD

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.