OTUB1 monoclonal Antibody | MB64323

OTUB1 monoclonal Antibody | MB64323 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:150

Background: The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: OTU deubiquitinase, ubiquitin aldehyde binding 1

Molecular Weight: 31.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HSPC263; OTB1; OTU1

Immunogen: Full length human recombinant protein of human OTUB1 (NP_060140) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A