OTUD6B Antibody (C-term) [APR05679G]

OTUD6B Antibody (C-term) [APR05679G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This OTUD6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the C-terminal region of human OTUD6B.

Cellular Localisation: N/A

Molecular Weight: 33813

Clone: Polyclonal

Gene Name: OTUD6B (HGNC:24281)

Gene ID: 51633

Function: [Isoform 1]: Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 (PubMed:21267069, PubMed:27864334) . May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation (PubMed:27864334) . May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation (PubMed:27864334) . May also play a role in proteasome assembly and function (PubMed:28343629) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: FC, WB

Dilution: WB--1:1000 FC--1:10~50

Synonyms: OTU domain-containing protein 6B, DUBA-5, OTUD6B, DUBA5