Description
OXA-01 is an ATP-competitive, selective dual inhibitor of mTORC1/mTORC2. Displays antiangiogenic and antitumor properties.
OXA-01 is an ATP-competitive, selective dual inhibitor of mTORC1/mTORC2. Displays antiangiogenic and antitumor properties.
Alternate Name/Synonyms: trans-4-[8-Amino-1-(7-chloro-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-cyclohexanecarboxylic acid
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 936889-68-8
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₀ClN₅O₂
Molecular Weight: 409.87
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective dual inhibitor of mTORC1/mTORC2.
MDL Number: N/A
PubChem CID: 45276387
SMILES: C1CC(CCC1C2=NC(=C3N2C=CN=C3N)C4=CC5=C(N4)C(=CC=C5)Cl)C(=O)O
InChi: InChI=1S/C21H20ClN5O2/c22-14-3-1-2-13-10-15(25-16(13)14)17-18-19(23)24-8-9-27(18)20(26-17)11-4-6-12(7-5-11)21(28)29/h1-3,8-12,25H,4-7H2,(H2,23,24)(H,28,29)
InChi Key: UXCAKZGNKOZXBM-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |