OXT Antibody | 15-970

OXT Antibody | 15-970 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human OXT (NP_000906.1) .

Research Area: Neuroscience

Tested Application: WB, IHC

Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: A549

Positive Control 2: NCI-H460

Positive Control 3: LO2

Positive Control 4: HepG2

Positive Control 5: Mouse liver

Positive Control 6: Rat liver

Molecular Weight: Observed: 13kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: oxytocin-neurophysin I, preproprotein, oxytocin-neurophysin I, OT-NPI, OT, MGC126892, MGC126890, oxytocin, prepro- (neurophysin I) , OXT

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.