p16-INK4A (S152) Antibody [ApR04823G]

p16-INK4A (S152) Antibody [ApR04823G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This p16-INK4A (S152) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from human p16-INK4A.

Cellular Localisation: Cytoplasm. Nucleus

Molecular Weight: 16533

Clone: Polyclonal

Gene Name: CDKN2A (HGNC:1787)

Gene ID: 1029

Function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Summary: Tissue Location: Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3, Cyclin-dependent kinase 4 inhibitor A, CDK4I, Multiple tumor suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2A, CDKN2, MTS1