P2RX4 Antibody | 22-402

P2RX4 Antibody | 22-402 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 55-338 of human P2RX4 (NP_002551.2) .

Research Area: Cell Cycle, Neuroscience

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:10 - 1:100

Specificiy: N/A

Positive Control 1: 22Rv1

Positive Control 2: Mouse kidney

Positive Control 3: Mouse lung

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 62kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: purinoceptor P2X4, purinergic receptor P2X4, purinergic receptor P2X ligand-gated ion channel 4, P2X receptor, subunit 4, P2X purinoceptor 4, ATP-gated cation channel protein, ATP receptor, purinergic receptor P2X, ligand-gated ion channel, 4, P2RX4, P2X4R, P2X4

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.