PABPC1 Antibody | 25-606

PABPC1 Antibody | 25-606 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PABPC1.

Research Area: Cancer

Tested Application: E, WB

Application: PABPC1 antibody can be used for detection of PABPC1 by ELISA at 1:1562500. PABPC1 antibody can be used for detection of PABPC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 71 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by peptide affinity chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store PABPC1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: PABPC1, PAB1, PABP, PABP1, PABPC2, PABPL1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The poly (A) -binding protein (PABP) , which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1) , inducible PABP (iPABP, or PABPC4; MIM 603407) , and PABP3 (PABPC3; MIM 604680) . In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly (A) -binding protein (PABP) , which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1) , inducible PABP (iPABP, or PABPC4; MIM 603407) , and PABP3 (PABPC3; MIM 604680) . In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.