PADI4 Polyclonal Antibody | E-AB-52164

PADI4 Polyclonal Antibody | E-AB-52164 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: EC 3.5.3.15, HL 60 PAD, HL-60 PAD, PAD 4, PAD, PADI 4, PADI 5, PADI H protein, Padi4, PADI4, PADI5, PDI 4, PDI 5, PDI4, PDI5, Peptidyl arginine deiminase type IV, Peptidyl arginine deiminase type V, Peptidylarginine deiminase IV, Protein arginine deiminase, Protein arginine deiminase type 4, Protein arginine deiminase type IV, Protein-arginine deiminase type IV, Protein-arginine deiminase type-4

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Background: This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human PADI4

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 74 kDa

Molecular Weight(Observed): Refer to figures