PADI6 Antibody (N-term) [APR31666G]

PADI6 Antibody (N-term) [APR31666G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This PADI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-223 amino acids from the N-terminal region of human PADI6.

Cellular Localisation: Cytoplasm. Nucleus {ECO:0000250|UniProtKB:Q8K3V4}. Cytoplasmic vesicle, secretory vesicle, Cortical granule {ECO:0000250|UniProtKB:Q8K3V4}. Note=Predominantly cytoplasmic (oocyte cytoplasmic sheets), also nuclear. Released extracellularly during the cortical reaction, and remains associated with the blastomeres surfaces as a peripheral membrane protein until the blastocyst stage of development. {ECO:0000250|UniProtKB:Q8K3V4}

Molecular Weight: 77727

Clone: Polyclonal

Gene Name: PADI6

Gene ID: 353238

Function: Catalyzes the deimination of arginine residues of proteins (By similarity) . May be involved in cytoskeletal reorganization in the egg and early embryo (PubMed:27545678) .

Summary: Tissue Location: Highly expressed in oocytes and weakly expressed in other somatic tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein-arginine deiminase type-6, Peptidyl arginine deiminase-like protein, Peptidylarginine deiminase VI, hPADVI, Protein-arginine deiminase type VI, PADI6