PAIP1 Antibody (N-term) [APR31753G]

PAIP1 Antibody (N-term) [APR31753G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PAIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human PAIP1.

Cellular Localisation: Cytoplasm.

Molecular Weight: 53525

Clone: Polyclonal

Gene Name: PAIP1 (HGNC:16945)

Gene ID: 10605

Function: Acts as a coactivator in the regulation of translation initiation of poly (A) -containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA- binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, PAIP-1, Poly (A) -binding protein-interacting protein 1, PAIP1