Pamidronate disodium | 1884

A bisphosphonate compound that inhibits bone resorption, the natural, ongoing process of bone being destroyed by osteoclasts. Also inhibits farnesyl diphosphate synthase (IC₅₀ = 200 nM).

Pamidronate disodium is a bisphosphonate compound that inhibits bone resorption, the natural, ongoing process of bone being destroyed by osteoclasts. Also inhibits farnesyl diphosphate synthase (IC₅₀ = 200 nM).

1884 | Pamidronate disodium DataSheet

Alternate Name/Synonyms: 3-Amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid, disodium salt

Appearance: White solid

Formulation: N/A

CAS Number: 57248-88-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃H₉NO₇P₂Na₂

Molecular Weight: 279.03

Cell-Permeable?: No

Purity: ≥98%

Solubilities: H₂O (~ 25 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An inhibitor of bone resorption

MDL Number: MFCD11045314

PubChem CID: 73351

SMILES: C(CN)C(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+]

InChi: InChI=1S/C3H11NO7P2.2Na/c4-2-1-3(5,12(6,7)8)13(9,10)11;;/h5H,1-2,4H2, (H2,6,7,8)(H2,9,10,11);;/q;2*+1/p-2

InChi Key: CEYUIFJWVHOCPP-UHFFFAOYSA-L