Description
PAN3 Antibody | 61-731 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Homology: Predicted species reactivity based on immunogen sequence: Mouse
Immunogen: This PAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 771-799 amino acids from the C-terminal region of human PAN3.
Research Area: Other
Tested Application: WB, IHC-P, Flow
Application: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 96 kDa
Validation: N/A
Isoform: N/A
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality: Polyclonal
Clone: N/A
Isotype: Rabbit Ig
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: batch dependent
Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}, PAB1P-dependent poly (A) -nuclease {ECO:0000255|HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255|HAMAP-Rule:MF_03181}, hPan3, PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: PAN3 is functions in cytoplasmic mRNA decay. It is as part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity.