PARP16 Antibody (C-term) [APR32273G]

PARP16 Antibody (C-term) [APR32273G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PARP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PARP16.

Cellular Localisation: Endoplasmic reticulum membrane; Single-pass type IV membrane protein

Molecular Weight: 36383

Clone: Polyclonal

Gene Name: PARP16 {ECO:0000303|PubMed:20106667, ECO:0000312|HGNC:HGNC:26040}

Gene ID: 54956

Function: Intracellular mono-ADP-ribosyltransferase that may play a role in different processes through the mono-ADP-ribosylation of proteins involved in those processes (PubMed:23103912, PubMed:22701565, PubMed:25043379) . May play a role in the unfolded protein response (UPR), by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors (PubMed:23103912) . May also mediate mono-ADP- ribosylation of karyopherin KPNB1 a nuclear import factor (PubMed:22701565) . May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases (PubMed:22701565) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Mono [ADP-ribose] polymerase PARP16, ADP-ribosyltransferase diphtheria toxin-like 15, Poly [ADP-ribose] polymerase 16, PARP-16, PAR16