PCBD1 Antibody (Center) [APR10902G]

PCBD1 Antibody (Center) [APR10902G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This PCBD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-37 amino acids from the Central region of human PCBD1.

Cellular Localisation: Cytoplasm. Nucleus. Note=Recruited to the nucleus through the interaction with HNF1B.

Molecular Weight: 12000

Clone: Polyclonal

Gene Name: PCBD1

Gene ID: 5092

Function: Involved in tetrahydrobiopterin biosynthesis (By similarity) . Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription (By similarity) . Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (By similarity) . Also acts as a coactivator for HNF1B-dependent transcription (PubMed:24204001) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, DCoH, Dimerization cofactor of HNF1, Phenylalanine hydroxylase-stimulating protein, Pterin carbinolamine dehydratase, PCD, PCBD1, DCOH, PCBD