PCDH15 Antibody | 13-421

PCDH15 Antibody | 13-421 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_001136235.1) .

Research Area: Other

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200

Specificiy: N/A

Positive Control 1: SH-SY5Y

Positive Control 2: 293T

Positive Control 3: A-549

Positive Control 4: Raji

Positive Control 5: Mouse brain

Positive Control 6: Mouse liver

Molecular Weight: Observed: 100kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PCDH15, RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F) . Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.