PCK1 Polyclonal Antibody | E-AB-40269

PCK1 Polyclonal Antibody | E-AB-40269 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: cytosolic [GTP], GTP, PCK1, PCKGC, PEP carboxykinase, PEPCK-C, PEPCK1, PEPCKC, Phosphoenolpyruvate carboxykinase 1 (soluble), Phosphoenolpyruvate carboxykinase 1, Phosphoenolpyruvate carboxykinase, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], Phosphoenolpyruvate carboxykinase, cytosolic, Phosphoenolpyruvate carboxylase, Phosphopyruvate carboxylase

Application: IHC

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Background: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Rat Phosphoenolpyruvate carboxykinase, cytosolic [GTP] protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Antigen Affinity Purification

Dilution: IHC 1:100-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A