PCNA, Human Recombinant | P1562

PCNA (Proliferating Cell Nuclear Antigen) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, Sphase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by UV irradiation, growth factors and eventually by neighbouring tumours. Recombinant human PCNA, was expressed in E. coli and purified by conventional chromatography techniques.

P1562 | PCNA, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: Proliferating cell nuclear antigen, MGC8367, Proliferating cell nuclear antigen, Proliferating cell nuclear antigen, PCNA

Alternates names: Proliferating cell nuclear antigen, MGC8367, Proliferating cell nuclear antigen, Proliferating cell nuclear antigen, PCNA

Taglines: A processivity factor for DNA polymerase δ

NCBI Gene ID #: 5111

NCBI Gene Symbol: PCNA

Gene Source: Human

Accession #: P12004

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGE: >95%

Assay: SDS - PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

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Binding Capacity:

Unit Definition:

Molecular Weight: 28 kDa

Concentration:

Appearance: Liquid

Physical form description: Liquid

Reconstitution Instructions:

Amino acid sequence: aa 1-261

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans