PD-1 (PDCD1) monoclonal Antibody | MB64395

PD-1 (PDCD1) monoclonal Antibody | MB64395 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse

Application: FC, IF, Neutralize, WB

Application Range: WB 1:2000, IF 1:100, FLOW 1:50

Background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: programmed cell death 1

Molecular Weight: 29.2 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2

Immunogen: Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A