PDCD6 polyclonal Antibody | BS8354

PDCD6 polyclonal Antibody | BS8354 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB,IHC,IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: An increased intracellular Ca2+ concentration induces apoptotic cell death. Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge. ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PDCD6 polyclonal Antibody detects endogenous levels of PDCD6 protein.

Molecular Weight: ~ 16 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Programmed cell death protein 6; Apoptosis-linked gene 2 protein; Probable calcium-binding protein ALG-2; PDCD6; ALG2

Immunogen: Recombinant full length Human PDCD6.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: