PDE1A polyclonal Antibody | BS71495

PDE1A polyclonal Antibody | BS71495 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) /calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PDE1A polyclonal Antibody detects endogenous levels of PDE1A protein.

Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HCAM1; HCAM-1; HSPDE1A; CAM-PDE-1A;

Immunogen: Recombinant protein of human PDE1A

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: