PDE1B polyclonal Antibody | BS6688

PDE1B polyclonal Antibody | BS6688 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background: Human PDE1B (PDE1B1) protein is present in neuronal cells of the cerebellum, hippocampus, and caudate, and lymphoblastoid lines, such as RPMI-8392 cells. PDE1B may participate in learning, memory, and regulation of phosphorylation of DARPP-32 in dopaminergic neurons. A splice variant known as PDE1B2 encodes a 516-amino acid protein and diverges from PDE1B1 by the replacement of the first 38 residues with an alternative 18 residues. The human PDE1B gene maps to chromosome 12q13, contains 13 exons, and encodes a 536 amino acid protein.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PDE1B polyclonal Antibody detects endogenous levels of PDE1B protein.

Molecular Weight: ~ 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 5''-cyclic nucleotide phosphodiesterase 1B; 63 a Cam PDE; 63 a Cam-PDE; Calcium/calmodulin dependent 3' 5' cyclic nucleotide Phosphodiesterase 1B; Calcium/calmodulin stimulated cyclic nucleotide phosphodiesterase; Calcium/calmodulin-dependent 3''; Calcium/calmodulin-dependent 3'5'-cyclic nucleotide Phosphodiesterase 1B; Calmodulin stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; Cam-PDE 1B; PDE 1B; PDE1B; PDE1B; PDE1B1; PDES 1B; PDES1B; Phosphodiesterase 1B; Phosphodiesterase

Immunogen: Recombinant full length Human PDE1B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: