PDTC | 1676

An antioxidant and an inhibitor of NF-kB; prevents induction of nitric oxide synthase (NOS) by inhibiting translation of NOS mRNA; induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells. Also inhibits breast cancer stem-like cells by blocking the NF-kB activity in MCF7 sphere and MCF7 cells.

PDTC is an antioxidant and an inhibitor of NF-kB; prevents induction of nitric oxide synthase (NOS) by inhibiting translation of NOS mRNA; induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells.

1676 | PDTC DataSheet

Alternate Name/Synonyms: Pyrrolidinedithiocarbamate Ammonium; PDC; APDC

Appearance: White solid

Formulation: N/A

CAS Number: 5108-96-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₉NS₂.NH₃

Molecular Weight: 164.28

Cell-Permeable?: No

Purity: ≥98%

Solubilities: DMSO (15 mg/ml) and H₂O (1 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A NF-kappaB inhibitor

MDL Number: MFCD00012720

PubChem CID: 517348

SMILES: C1CCN(C1)C(=S)[S-].[NH4+]

InChi: InChI=1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3

InChi Key: MDDIUTVUBYEEEM-UHFFFAOYSA-N