PE mouse anti-human CD28 monoclonal Antibody | MB8503P

PE mouse anti-human CD28 monoclonal Antibody | MB8503P | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Application: FC

Application Range: FC:5ul per test

Background: CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular) . CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs) . The CD86 expression on antigen presenting cells is constitutive (expression is independent of environmental factors) .CD28 is the only B7 receptor constitutively expressed on naive T cells. Association of the TCR of a naive T cell with MHC:antigen complex without CD28:B7 interaction results in a T cell that is anergic.

Storage & Stability: Store at 4°C . Avoid freezed.

Specificity: This Antibody detects Extracellular domain of human CD28.

Molecular Weight: N/A

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: N/A

Immunogen: N/A

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified

Pathway: