Pemafibrate, Free Acid | B2670

Pemafibrate free acid (K877) is a selective peroxisome proliferator-activated receptor-α (PPAR-α) modulator and a next-generation PPAR-α agonist. It activated PPAR-α, PPAR-γ, and PPAR-δ with EC₅₀ values of 1 nM, 2.3 µM, and 1 µM, respectively.

Pemafibrate free acid (K877) is a selective peroxisome proliferator-activated receptor-α (PPAR-α) modulator and a next-generation PPAR-α agonist. It activated PPAR-α, PPAR-γ, and PPAR-δ with EC₅₀ values of 1 nM, 2.3 µM, and 1 µM, respectively.

B2670 | Pemafibrate, Free Acid DataSheet

Alternate Name/Synonyms: (R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid,Pemafibrate,K877,(R)-K 13675

Appearance: Crystalline solid

Formulation:

CAS Number: 848259-27-8

Structure Available?: Yes

Peptide sequence:

Salt Form: No

Molecular Formula: C₂₈H₃₀N₂O₆

Molecular Weight: 490.55

Cell-Permeable?: True

Purity: ≥98%

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A selective peroxisome proliferator-activated receptor [alpha] (PPAR[alpha]) modulator

MDL Number:

PubChem CID: 11526038

SMILES: CCC(C(=O)O)OC1=CC=CC(=C1)CN(CCCOC2=CC=C(C=C2)OC)C3=NC4=CC=CC=C4O3

InChi: InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1

InChi Key: ZHKNLJLMDFQVHJ-RUZDIDTESA-N