Additional Information
Short Description: |
Folate-dependent enzyme inhibitor |
Research Area: |
Cancer, Apoptosis |
Alternative Name(s): |
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium salt; LY231514 |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
357166-29-1 |
Molecular Formula: |
C20H19N5Na2O6 [7H2O] |
Molecular Weight: |
597,5 |
Source: |
Synthetic |
Purity: |
>98% (TLC, HPLC); NMR (Conforms) |
Solubility: |
May be dissolved in Water (100 mg/ml) |
Appearance: |
White powder |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.O.O.[Na+].[Na+] |
InChI: |
InChI=1S/C20H21N5O6.2Na.7H2O/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;;;;;;;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;;7*1H2/q;2*+1;;;;;;;/p-2/t13-;;;;;;;;;/m0...... |
InChIKey: |
QJVSMHJWAOSBMD-MYXYZBIASA-L |
Field of Use: |
For in vitro research use only. |
Related Products
Pemetrexed (disodium hemipenta hydrate)
840
NULL226.00
Pemetrexed (disodium hemipenta hydrate)
840-HY-13781-GEN
Pemetrexed | B1862
26
NULL339.00 - NULL650.00
Pemetrexed is a high affinity dihydrofolate reductase (DHFR) inhibitor (Ki = 7 nM). Also inhibits thymidylate synthase, AICART and glycinamide ribonucleotide formyltransferase (Ki values are 109 nM,...
26-B1862-GEN
