PER1 polyclonal Antibody | BS71237

PER1 polyclonal Antibody | BS71237 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC IF

Application Range: WB: 1:500 - 1:2000 IHC: 1:50 - 1:100 IF: 1:50 - 1:200

Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PER1 polyclonal Antibody detects endogenous levels of PER1 protein.

Molecular Weight: ~ 50 KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PER1;PER;RIGUI;Hper

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PER1 (NP_002607.2) .

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A