Periostin/OSF-2, human recombinant | 4204

Periostin was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor 1 (TGF-1) and bone morphogenetic protein (BMP-2). Abnormal expression of periostin is also linked to angiogenesis and metastasis in epithelial tumors. ’s Periostin is a His-Tagged fusion protein produced in E. coli, containing 648 amino acid residues of the human Periostin and 23 additional amino acid residues - HisTag, Xa - cleavage site.

4204 | Periostin/OSF-2 human recombinant DataSheet

Biomolecule/Target: Periostin/OSF-2

Synonyms: OSF-2, Periostin, Osteoblast Specific Factor 2, PN OSF-2,PDLPOSTN, POSTN, MGC119510, MGC119511, PN, RP11-412K4.1.

Alternates names: p40 cytokine, T-cell growth factor p40

Taglines: A ligand for integrins

NCBI Gene ID #: 116558

NCBI Gene Symbol: IL9

Gene Source: Rat

Accession #: D4A8I9

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Measured by its ability to enhance MC/9 cell proliferation.

Biological activity: Measured by its ability to enhance MC/9 cell proliferation.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: ~14.3 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: MQRCSTSWGI QHTSYLIENL KDDPSSKCSC SANVTSCLCL PIPSDDCTTP CFQEGMSQVT NATQQSKFSP FFFRVKRIVE TLKSNKCQFF SCEKPCNQTT AGNTVSFLKS LLKTFQKTEV QVQRSRA