Periostin (Periostin) monoclonal Antibody | MB64459

Periostin (Periostin) monoclonal Antibody | MB64459 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, WB

Application Range: WB 1:500, IF 1:100

Background: Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1 (TGF beta 1) and bone morphogenetic protein (BMP2) . Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: periostin

Molecular Weight: 93.2 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: OSF-2; OSF2; PDLPOSTN; PN

Immunogen: Human recombinant protein fragment corresponding to amino acids 1-230 of human periostin (NP_006466) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A