PEX3 (IN) Antibody | 9667

PEX3 (IN) Antibody | 9667 | Gentaur UK, US & Europe Distribution

Product Type: Primary Antibodies

Category: Primary Antibodies, Polyclonal Antibodies, Signal Transduction Antibodies

Research Area: Signal Transduction

Type: Polyclonal

Host Species: Rabbit

Reactivity Species: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: monkey (100%), cow (100%), chicken (100%)

Immunology: Anti-PEX3 antibody (9667) was raised against a peptide corresponding to 14 amino acids near the center of human PEX3. The immunogen is located within the center of PEX3.

Tested Application: E, WB, IF

Application Note: WB: 2 μg/mL; IF: 20 μg/mL. Antibody validated: Western Blot in human, mouse and rat samples; Immunofluorescence in human, mouse and rat samples. All other applications and species not yet tested.

Positive Control 1: Cat. No. 1203 – A549 Cell Lysate

Positive Control 2: Cat. No. 17-003 – A549 Cell Slide

Predicted Molecular Weight: Predicted: 42kD

Observed: 42 kD

Isoform: Human PEX3 has 1 isoform, (373aa, 42kD) . Mouse PEX3 has 1 isoform (372aa, 42kD) . Rat PEX3 has one isoform (372aa, 42kD) . 9667 can detect PEX3 in human, mouse and rat.

Purification: PEX3 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PEX3 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage: PEX3 antibody can be stored at 4 ˚C for three months and -20 ˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Names: PEX3 Antibody: Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3

Protein Accession: P56589

User Note: Optimal dilutions for each application to be determined by the researcher.

Background: PEX3 Antibody: PEX3 is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, PEX3 is necessary for the import of peroxisomal membrane proteins in the peroxisomes. Thus within the cell, PEX3 is stabilized by PEX19 preventing PEX3 aggregation. Mutations in the PEX19-binding domain of PEX3 reduce the affinity for PEX19 and destabilize PEX3.

Loading Controls: N/A

Source: N/A

Purity: N/A

CAS: N/A

Shipping Condition: N/A