PFKM Polyclonal Antibody | E-AB-18753

PFKM Polyclonal Antibody | E-AB-18753 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 6 Phosphofructokinase Muscle Type, 6-phosphofructokinase, 6-phosphofructokinase muscle type, EC 2.7.1.1, EC 2.7.1.11, GSD7, K6PF, MGC8699, muscle type, PFK, muscle type, PFK-A, PFKA, PFKL, PFKM, PFKP, PFKX, Phosphofructo 1 Kinase Isozyme A, Phosphofructo-1-kinase isozyme A, Phosphofructokinase 1, Phosphofructokinase M, Phosphofructokinase, muscle, Phosphofructokinase, muscle type, Phosphofructokinase, polypeptide X, Phosphofructokinase-M, Phosphohexokinase

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Concentration: 1.02 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human PFKM

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 85 kDa

Molecular Weight(Observed): Refer to figures