PGCC1 Antibody | 5309

PGCC1 Antibody | 5309 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (92%)

Immunogen: PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1.
The immunogen is located within the last 50 amino acids of PGCC1.

Research Area: Stem Cell

Tested Application: E, WB

Application: PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Specificiy: This antibody will not cross-react with FAM120A.

Positive Control 1: Cat. No. 1471 - Rat Thymus Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: PGCC1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PGCC1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: PGCC1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: PGCC1 Antibody: CCPG, PGCC1, KIAA1838, dJ894D12.1, CCPG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, PPARG constitutive coactivator 1, Constitutive coactivator of PPAR-gamma

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B) , is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.