PGK1 Antibody (Center) [AMM04370G]

PGK1 Antibody (Center) [AMM04370G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the Central region of human PGK1.

Cellular Localisation: Cytoplasm.

Molecular Weight: 44615

Clone: Polyclonal

Gene Name: PGK1

Gene ID: 5230

Function: Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1, 3- diphosphoglycerate to 3-phosphoglycerate (PubMed:30323285, PubMed:7391028) . In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (PubMed:2324090) . May play a role in sperm motility (PubMed:26677959) .

Summary: Tissue Location: Mainly expressed in spermatogonia. Localized on the principle piece in the sperm (at protein level) . Expression significantly decreased in the testis of elderly men

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, IF, FC, WB

Dilution: IHC-P--1:100 WB--1:1000 IHC-P--1:100~500 IF--1:10~50 FC--1:10~50

Synonyms: Phosphoglycerate kinase 1, Cell migration-inducing gene 10 protein, Primer recognition protein 2, PRP 2, PGK1, PGKA