PGLYRP4 Antibody (Center) [APG02965G]

PGLYRP4 Antibody (Center) [APG02965G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PGLYRP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the Central region of human PGLYRP4.

Cellular Localisation: Secreted.

Molecular Weight: 40620

Clone: Polyclonal

Gene Name: PGLYRP4

Gene ID: 57115

Function: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.

Summary: Tissue Location: Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level) . High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Peptidoglycan recognition protein 4, Peptidoglycan recognition protein I-beta, PGLYRPIbeta, PGRP-I-beta, Peptidoglycan recognition protein intermediate beta, PGLYRP4, PGRPIB