PGR Monoclonal Antibody | E-AB-22105

PGR Monoclonal Antibody | E-AB-22105 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, PRGR, Progesterone receptor, Progestin receptor form A, Progestin receptor form B

Application: IHC-p, IF

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Background: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: IHC 1:100-1:300, IF 1:100-200

Clone: Clone:1A5

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A