Additional Information
Short Description: |
MET kinase inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
Alternative Name(s): |
(2R)-1-[[5-[(Z)-[5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2-(1-pyrrolidinylmethyl)pyrrolidine |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
477575-56-7 |
Molecular Formula: |
C32H34Cl2N4O4S |
Molecular Weight: |
641,61 |
Source: |
Synthetic |
Purity: |
>98 |
Solubility: |
Soluble to 100 mM in DMSO. |
Appearance: |
Yellow solid |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
ClC1=C(C(=CC=C1)Cl)C[S](=O)(=O)C3=CC=C2NC(C(/C2=C3)=C\C4=C(C(=C([NH]4)C)C(=O)N5CCC[C@@H]5CN6CCCC6)C)=O |
InChI: |
InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1 |
InChIKey: |
OYONTEXKYJZFHA-SSHUPFPWSA-N |
Field of Use: |
For in vitro research use only. |
Related Products
PHA-665752 | B2057
26
NULL403.00 - NULL1,059.00
PHA-665752 is a potent, selective and ATP-competitive inhibitor of MET kinase (IC₅₀ values are 9, 68, 200, 1400, 3000, 3800 and 6000 nM for MET, Ron, Flk-1, c-abl, FGFR1, EGFR and c-src respectively...
26-B2057-GEN
PHA-665752 | E1KS1070
426
NULL476.00
PHA-665752 | E1KS1070 | Gentaur UK, US & Europe Distribution
426-E1KS1070
