PHB2 polyclonal Antibody | BS70635

PHB2 polyclonal Antibody | BS70635 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB,IHC,IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: PHB2 (Prohibitin 2) is a Protein Coding gene. Diseases associated with PHB2 include marinesco-sjogren syndrome and urethritis. Among its related pathways are Akt Signaling Pathway and GPCR Pathway. GO annotations related to this gene include estrogen receptor binding. Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity) . Functions as an estrogen receptor (ER) -selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PHB2 polyclonal Antibody detects endogenous levels of PHB2 protein.

Molecular Weight: ~ 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BAP; REA; p22; hBAP; Bap37; BCAP37; PNAS-141; D-prohibitin; Prohibitin-2; Prohibitin 2; Prohibitin2;

Immunogen: Recombinant protein of human PHB2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Notch Signaling,Contribution of Soluble Factors to EMT,ErbB HER Signaling,