PHF14 Antibody | 7485

PHF14 Antibody | 7485 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: PHF14 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHF14.
The immunogen is located within amino acids 210 - 260 of PHF14 .

Research Area: Stem Cell

Tested Application: E, WB, IF

Application: PHF14 antibody can be used for detection of PHF14 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: PHF14 antibody is human, mouse and rat reactive. Multiple isoforms of PHF14 are known to exist.

Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate

Positive Control 2: Cat. No. 17-010 - HEK293 Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 98 kDa
Observed: 100kDa

Validation: N/A

Isoform: N/A

Purification: PHF14 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PHF14 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: PHF14 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: PHF14 Antibody : KIAA0783, PHD finger protein 14

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: PHF14, a novel plant homology domain (PHD) transcription factor, controls the proliferation of mesenchymal cells by regulating PDGFR alpha expression in embryonic development (1) . PHD finger transcription factors are concerned with transcriptional regulation by interacting with modified histones (2) , and dysregulation of several genes encoding PHD finger transcription factors, such as ING1 and RBP2, has been found in human cancer diseases suggesting these factors have an important role for cancer cell proliferation. PHF14 is a potential target for new treatments of lung fibrosis (1, 3) .