Phospho-Btk(Y223) Polyclonal Antibody | E-AB-68088

Phospho-Btk(Y223) Polyclonal Antibody | E-AB-68088 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA, BTK

Application: IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology, Signal Transduction

Background: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic phosphorylated peptide around Y223 of human Btk (NP_000052.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: IF 1:20-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A