Phospho-eIF2α(S51) Polyclonal Antibody | E-AB-68134

Phospho-eIF2α(S51) Polyclonal Antibody | E-AB-68134 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, EIF2S1

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A phospho specific peptide corresponding to residues surrounding S51 of human EIF2S1

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 36 kDa

Molecular Weight(Observed): 38 kDa