Phospho EIF4EBP1 (Thr36) Antibody | A1945

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multi-subunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

A1945 | Phospho EIF4EBP1 (Thr36) Antibody DataSheet

Antibody Target: Phospho EIF4EBP1 (Thr36)

Target Alternative Name: EIF4EBP1; 4E-BP1; 4EBP1; BP-1; PHAS-I; eukaryotic translation initiation factor 4E-binding protein 1

Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of EIF4EBP1 at Thr36 in human, mouse and rat samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Rat, Mouse, Human

Immunogen Sequence: A phospho specific peptide corresponding to residues surrounding Thr36 of human EIF4EBP1

Accession #: Q13541

Gene ID: 1978

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purified

Application: Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False