phospho-FHOD1 (Thr1141) Polyclonal Antibody | BS65747

phospho-FHOD1 (Thr1141) Polyclonal Antibody | BS65747 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,

Application: WB,

Application Range: WB=1:500-2000

Background: The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: phospho-FHOD1 (Thr1141) Polyclonal Antibody detects endogenous levels of FHOD1 protein only when phosphorylated at Thr1141.

Molecular Weight: 126 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FHOD1 (phospho T1141) ; p-FHOD1 (phospho T1141) ; FH1/FH2 domain containing protein; FH1/FH2 domain-containing protein 1; Fhod1; FHOD1_HUMAN; FHOS; FHOS1; Formin homolog overexpressed in spleen 1; Formin homology 2 domain containing 1; Formin homology 2 domain containing protein 1; Formin homology 2 domain-containing protein 1.聽聽

Immunogen: KLH conjugated synthesised phosphopeptide derived from human FHOD1 around the phosphorylation site of Thr1141:RR (p-T) LK

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: affinity purified by Protein A

Pathway: