Phospho HDAC5 (Ser498) Antibody | A1955

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

A1955 | Phospho HDAC5 (Ser498) Antibody DataSheet

Antibody Target: Phospho HDAC5 (Ser498)

Target Alternative Name: KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9

Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of HDAC5 at Ser498 in human, mouse, rat, bovine and porcine samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Bovine, Porcine, Rat, Mouse, Human

Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the center region of human HDAC5.

Accession #: Q9UQL6

Gene ID: 10014

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: True

Immunofluorescence Verified: True

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False