Phospho-Histone H2A(S129) Polyclonal Antibody | E-AB-68242

Phospho-Histone H2A(S129) Polyclonal Antibody | E-AB-68242 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: H2A1, SPT11

Application: IHC

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A