Phospho-HUMAN-PIK3C2B (Y228) Antibody [AMM07128G]

Phospho-HUMAN-PIK3C2B (Y228) Antibody [AMM07128G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 215-250 amino acids from human.

Cellular Localisation: Microsome. Cell membrane. Cytoplasm, cytosol Nucleus. Endoplasmic reticulum. Note=Found mostly in the microsome, but also in the plasma membrane and cytosol. Nuclear in testis

Molecular Weight: 184768

Clone: Polyclonal

Gene Name: PIK3C2B

Gene ID: 5287

Function: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns (PubMed:10805725, PubMed:9830063, PubMed:11533253) . Does not phosphorylate PtdIns (4, 5) P2 (PubMed:9830063) . May be involved in EGF and PDGF signaling cascades (PubMed:10805725) .

Summary: Tissue Location: Expressed in columnar and transitional epithelia, mononuclear cells, and ganglion cells (at protein level) . Widely expressed, with highest levels in thymus and placenta and lowest in peripheral blood, skeletal muscle and kidney

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta, PIK3C2B